Aditya Jyot Explore Clinical Research

Clinical Research

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About AJIOVSAR

Aditya Jyot Institute of Vision Sciences and Research [AJIOVSAR]

Established in 2011, AJIOVSAR is academics, research and development unit of Aditya Jyot Eye Hospital Pvt. Ltd. Aditya Jyot Eye Hospital strives to provide world-class eye care service under one roof with innovative service through research. This is where AJIOVSAR plays a crucial role in disseminating knowledge through academic programs and provide the latest treatment options through research.

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Our Mission

AJIOVSAR’s mission is to conduct high impact eye research with the aim to prevent blindness and major eye diseases globally.

Our Vision

To enhance ophthalmic and visual sciences in the country.

AJIOVSAR Research Team

Prof. Dr. S. Natarajan

Clinician Scientist

Dr.Nazimul Hussain

Virtual Director of Academics & Research

Dr. Shanta Motwani, India

Honorary Visiting Professors

AJIOVSAR research theme

Academic Research - In house Ongoing Projects:

To compare the incidence of raised intraocular pressure after uncomplicated vitreoretinal surgeries.

To evaluate the correlation between outer retinal layer thickness, central subfoveal thickness and disorganization of inner retinal layers to Best corrected visual acuity in Diabetic Macular Oedema.

To evaluate the anatomical and functional outcomes in patients with macular edema due to branch retinal vein occlusion with intravitreal ranibizumab, aflibercept and dexamethasone.

Comparison of the water drinking test and modified Diurnal Tension Curve results in primary open angle glaucoma patients on Latanoprost and Bimatoprost.

Clinical Research

We are the centre for clinical trials being conducted on indications such as uveitis, pathologic myopia, age-related macular degeneration and glaucoma.

Aditya Jyot Eye Hospital Ethics Committee

Sr. No. Name Qualification with Specialization Current Organization Telephone number, fax number, e-mail I.D. and mailing address Designation/Role of member in Ethics Committee Affiliation of member with institute that has constituted the ethics committee
1 Dr. Shirish Joshi MBBS (MD) Pharmacology, PGDCR Haffkine
1st floor, Seth G. S. Medical College and KEM hospital, Parel, Mumbai-400012 		91 98203 38456
shirishjoshi2002@yahoo.co.in 		Chairman Not Affiliated with Institute
2 Dr. Sandeep Nagvekar M.B.B.S. M.D. Ophthalmology , D.O.M.S. Nagvekar Eye Clinic, Swappani Building, Swami Vivekanand Marg, Opposite Tirupati Shopping Center, Santacruz West,
Mumbai, Maharashtra 400054 		+91-9820080497 Clinician Not Affiliated with Institute
3 Mrs. (Dr.)SuganthiIyer M.B.B.S. , LLB P. D. Hinduja Hospital and Medical Research Centre, Veer Savarkar Marg, Mahim, Mumbai-400 016 India. +91-9322280036 drsiyerin@yahoo.co.in Legal Expert Not Affiliated with Institute
4 Mr. Kirit Sanghavi HSC Arpan Eye Bank. 2,Poonam, 160, R.B.Mehta Marg Ghatkopar (E). Mumbai-400 077. Contact – 25060897 +91-9867761594, kgsanghvi1@yahoo.com Social Worker Not Affiliated with Institute
5 Mr. Satish Kulkarni B.Tech. (Chem.),IIT Bombay Parker Arte India, Printing House, 42, G.D. Ambekar Marg, Wadala,
Mumbai, 400031		 022-24181557,
022-66624981,
022-66624983,
+91-9820138678,
ksatish3@gmail.com 		Lay Person Not Affiliated with Institute
6 Mr. Kasiviswanathan Krishnan Electrical Engineer (B.E.) Retired from Nuclear Power Corporation, Mumbai 022-24028551,
kksikith@gmail.com 		Lay Person Not Affiliated with Institute
7 Dr. Shirish Joshi M.B.B.S.,M.D. Pharmacology, Post-graduate Diploma in Clinical Research & Trial Management Dept of Clinical Pharmacology, New MS Building, 1st Floor Seth GS Medical College and KEM Hospital Parel, Mumbai 400 012 022-24136051,
+91-9820338456,
Shirishjoshi2002@yahoo.co.in 		Pharmacologist Not Affiliated with Institute
8 Ms. Anurupa Balkrishnan B.Com, L.L.B. 12th Floor, Lloyds Gardens AppasahebMarathe Marg, Prabhadevi, Mumba- 400025 022-24326893, +91-9892208581 anurupabalakrishnan@gmail.com Legal Expert Not Affiliated with Institute
9 Dr. P.G. Gopalakrishnan M.com, M. Phil, LLM Retired from S.I.W.S., College, Wadala, Mumbai 022-25288746, pgg@vsnl.com, pgggk@yahoo.com Philosopher Not Affiliated with Institute

Ethics Committee for Clinical Research

Clinical Research Department 2nd floor, Aditya Jyot Eye Hospital Building Contact No:-24177632

Research Topics

  • Dry Eye
  • Uveitis
  • Age Related Macular Degeneration
  • Diabetic Retinopathy
  • Glaucoma

Ongoing Clinical Trails

Structured Post-marketing surveillance to collect the safety data of intravitreal aflibercept injection (IVT-AFL) in patients of wet age-related macular degeneration during real world clinical practice.

Completed Clinical Trials

Sr. No. Clinical Trial Status
1 To compare the safety and efficacy of Ranibizumab of Intas Biopharmaceuticals Ltd. in comparison with Lucentis in patients of wet Age-related Macular Degeneration. Completed
2 “UNravellingnAMD real-life clinical management and Outcome With intravitreal Ranibizumab injection – A retrospective analysis (UNCOVER )” Completed
3 A Prospective, Comparative, Assessor-Blind, Randomized, Multicentric Phase III study to compare the safety and efficacy of Ranibizumab of Intas Biopharmaceuticals Ltd. in comparison with Lucentis of Novartis in patients of wet AMD (Age-related Macular Degeneration. Completed
4 A 12 month, phase III, randomized, double-masked, multicenter, active-controlled study to evaluate the efficacy and safety of two individualized regimens of 0.5mg ranibizumab vs. verteporfin PDT in patients with visual impairment due to choroidal neovascularization secondary to pathologic myopia (Brilliance). Completed
5 A Pivotal phase II/III, randomized, double-masked, sham-controlled trial of QPI-1007 delivered by multi-dose intravitreal injections to subjects with acute Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION). Terminated
6 A randomized, multicenter, prospective, parallel group, double-blind, three arms, comparative study to compare the efficacy and safety of Brinzolamide 1% ophthalmic suspension of Cipla Ltd., India against Azopt® manufactured by Alcon Pharma Ltd., the US in subjects with chronic open-angle glaucoma or ocular hypertension. Terminated
7 To study the efficacy of Ranibizumab of Intas Pharmaceuticals Ltd. in patients with visual impairment. Completed
8 To collect safety data in patients with Wet-AMD after giving aflibercept injection in the affected eye. Ongoing